World Wires · story 84919 · corroborated · 1 source(s)

PKNs are required for cardiac hypertrophy induced by angiotensin II in mice

Of the three PKN isoforms, only homozygous Pkn2 knockout in mice is embryonic lethal; mice with Pkn2 haploinsufficiency or Pkn1/3 double knockout (Pkn1/3DK

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