World Wires · story 84555 · corroborated · 1 source(s)

DNA-PK enforces the S/G2 checkpoint in ATM-deficient cells to limit ATR inhibitor efficacy

ATR inhibition has been proposed as a strategy for tumors under replication stress or those harboring ATM deficiency. However, anti-tumor activity is limit

Open in the desk

Coverage

What this site indexes