World Wires · Story 43644 · corroborated · 1 Quelle(n)

A chemical perturbation scan on a K2P channel modulator pocket identifies affinity hotspots

Ion permeation in the two-pore-domain K+ (K2P) channel TREK1 is gated largely at the selectivity filter (SF), by a C-type-like inactivation mechanism invol

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