Epigenetic Mechanisms Inhibit Smad7 and Contribute to Fibrosis in Crohn's Disease
Background & Aims: TGF-beta1 is a central regulator of profibrotic gene expression, extracellular matrix deposition, and the development of intestinal fibr
Background & Aims: TGF-beta1 is a central regulator of profibrotic gene expression, extracellular matrix deposition, and the development of intestinal fibr